Invention Grant
- Patent Title: Azaindenoisoquinoline topoisomerase I inhibitors
- Patent Title (中): 偶氮异喹啉拓扑异构酶I抑制剂
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Application No.: US13548579Application Date: 2012-07-13
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Publication No.: US08686146B2Publication Date: 2014-04-01
- Inventor: Mark S. Cushman , Evgeny A. Kiselev , Andrew E. Morrell
- Applicant: Mark S. Cushman , Evgeny A. Kiselev , Andrew E. Morrell
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Barnes & Thornburg LLP
- Main IPC: C07D471/00
- IPC: C07D471/00 ; C07D221/22 ; A61K31/44
Abstract:
The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer.
Public/Granted literature
- US20140018360A1 AZAINDENOISOQUINOLINE TOPOISOMERASE I INHIBITORS Public/Granted day:2014-01-16
Information query
