Invention Grant
US08686121B2 Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
有权
包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
- Patent Title: Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
- Patent Title (中): 包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
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Application No.: US13120442Application Date: 2009-09-23
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Publication No.: US08686121B2Publication Date: 2014-04-01
- Inventor: Idit Shachar , Inbal Binsky , Mirko Sobotta
- Applicant: Idit Shachar , Inbal Binsky , Mirko Sobotta
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- International Application: PCT/IL2009/000919 WO 20090923
- International Announcement: WO2010/035259 WO 20100401
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K14/00
Abstract:
A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
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