Invention Grant
- Patent Title: Diazepan orexin receptor antagonists
- Patent Title (中): 二氮杂食欲素受体拮抗剂
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Application No.: US12225506Application Date: 2007-03-27
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Publication No.: US08685961B2Publication Date: 2014-04-01
- Inventor: Karen M. Brashear , Paul J. Coleman , Christopher D. Cox , Anthony M. Smith , David B. Whitman
- Applicant: Karen M. Brashear , Paul J. Coleman , Christopher D. Cox , Anthony M. Smith , David B. Whitman
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2007/007738 WO 20070327
- International Announcement: WO2007/126935 WO 20071108
- Main IPC: A61P3/04
- IPC: A61P3/04 ; A61K31/55 ; C07D243/08
Abstract:
The present invention is directed to diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20090124603A1 Diazepan Orexin Receptor Antagonists Public/Granted day:2009-05-14
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