Invention Grant
- Patent Title: Drug composition cytotoxic for pancreatic cancer cells
- Patent Title (中): 用于胰腺癌细胞的药物组合物细胞毒性
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Application No.: US13131840Application Date: 2009-11-30
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Publication No.: US08685941B2Publication Date: 2014-04-01
- Inventor: James Turkson
- Applicant: James Turkson
- Applicant Address: US FL Orlando
- Assignee: University of Central Florida Research Foundation, Inc.
- Current Assignee: University of Central Florida Research Foundation, Inc.
- Current Assignee Address: US FL Orlando
- Agency: Ballard Spahr LLP
- International Application: PCT/US2009/066079 WO 20091130
- International Announcement: WO2010/065444 WO 20100610
- Main IPC: A61K31/70
- IPC: A61K31/70

Abstract:
Disclosed herein are compositions comprising a drug combination that comprises ZD and S3I-201, Das and S3I-201, ZD and AG490, or Das and AG490. The disclosed drug combinations target two or more functional elements such as EGFR or Src and Stat3 or Jaks in pancreatic cancer cells. Also disclosed herein are methods of using the disclosed compositions to cytotoxically affect pancreatic cancer cells and methods of making the disclosed compositions.
Public/Granted literature
- US20110263525A1 DRUG COMPOSITION CYTOTOXIC FOR PANCREATIC CANCER CELLS Public/Granted day:2011-10-27
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