Invention Grant
- Patent Title: Medical methods and agents for use therein
- Patent Title (中): 用于其中的医疗方法和药剂
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Application No.: US13510565Application Date: 2010-11-17
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Publication No.: US08685640B2Publication Date: 2014-04-01
- Inventor: Thomas Tötterman , Linda Sandin , Angelica Loskog , Sara Mangsbo , Peter Ellmark
- Applicant: Thomas Tötterman , Linda Sandin , Angelica Loskog , Sara Mangsbo , Peter Ellmark
- Applicant Address: SE Lund
- Assignee: Alligator Bioscience AB
- Current Assignee: Alligator Bioscience AB
- Current Assignee Address: SE Lund
- Agency: Morrison & Foerster LLP
- Priority: GB0920258.1 20091119
- International Application: PCT/GB2010/002115 WO 20101117
- International Announcement: WO2011/061487 WO 20110526
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; G01N33/53
Abstract:
The present invention provides an immunomodulatory agent for use in the local treatment of tumors, wherein the treatment comprises patient-specific optimization of the dose of the immunomodulatory agent to identify the maximum therapeutic dose that does not induce an increase in the number of local regulatory T cells (Treg cells) in the patient The invention further provides methods for the local treatment of tumors as well as methods for optimising treatments for the same.
Public/Granted literature
- US20130004483A1 MEDICAL METHODS AND AGENTS FOR USE THEREIN Public/Granted day:2013-01-03
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