An instrument for reducing a spinal rod includes a reduction member sized and shaped to be positioned about an anchor extension connected to a bone anchor, an actuator assembly connected to the reduction member and operable to move the reduction member distally relative to the anchor extension along a longitudinal axis of the anchor extension, and a connection mechanism for removable and replaceable connection of the actuator assembly to a proximal end of the anchor extension. The connection mechanism is adjustable between a first position in which the connection mechanism connects the actuator assembly to the proximal end of the anchor extension and a second position in which the connection mechanism and the actuator assembly are released from the anchor extension.