Invention Grant
US08664408B2 Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it
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合成方法和4- {3- [顺式 - 六氢环戊并[c]吡咯-2（1H） - 基]]苯甲酰胺盐酸盐的结晶形式和含有它的药物组合物
![Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it](/docs/US/2014-03-04/US08664408B2/abs.jpg.600x600.jpg)
- Patent Title: Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it
- Patent Title (中): 合成方法和4- {3- [顺式 - 六氢环戊并[c]吡咯-2（1H） - 基]]苯甲酰胺盐酸盐的结晶形式和含有它的药物组合物
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Application No.: US13489691Application Date: 2012-06-06
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Publication No.: US08664408B2Publication Date: 2014-03-04
- Inventor: Nicolas Robert , Jean-Michel Lerestif , Jean-Pierre Lecouve , Marina Gaillard , Loic Meunier , Philippe Letellier , Mathieu Boiret
- Applicant: Nicolas Robert , Jean-Michel Lerestif , Jean-Pierre Lecouve , Marina Gaillard , Philippe Letellier , Mathieu Boiret , Julie Meunier
- Applicant Address: FR Suresnes Cedex
- Assignee: Les Laboratoires Servier
- Current Assignee: Les Laboratoires Servier
- Current Assignee Address: FR Suresnes Cedex
- Agency: Hueschen and Sage
- Priority: FR1101746 20110608
- Main IPC: C07D209/44
- IPC: C07D209/44 ; A61K31/40
![Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it](/abs-image/US/2014/03/04/US08664408B2/abs.jpg.150x150.jpg)
Abstract:
Industrial synthesis process for, and crystalline form I of, the compound of formula (I): and also crystalline form I of the associated free base. Medicinal products containing the same which are useful in the treatment of disorders of the histaminergic system.
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