Invention Grant
US08664401B2 N-linked hydroxamic acid derivatives useful as antibacterial agents
有权
用作抗菌剂的N-连接的异羟肟酸衍生物
- Patent Title: N-linked hydroxamic acid derivatives useful as antibacterial agents
- Patent Title (中): 用作抗菌剂的N-连接的异羟肟酸衍生物
-
Application No.: US13515607Application Date: 2010-12-06
-
Publication No.: US08664401B2Publication Date: 2014-03-04
- Inventor: Matthew Frank Brown , Ye Che , Anthony Marfat , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
- Applicant: Matthew Frank Brown , Ye Che , Anthony Marfat , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent John A. Wichtowski
- International Application: PCT/IB2010/055596 WO 20101206
- International Announcement: WO2011/073845 WO 20110623
- Main IPC: C07D401/00
- IPC: C07D401/00 ; A61K31/444
Abstract:
The present invention is directed to a new class of hydroxamic acid derivatives of formula I, wherein the variables G, T, D, L, R1, R2, R3 are as described herein, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections in a patient in need thereof.
Public/Granted literature
- US20120258948A1 N-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents Public/Granted day:2012-10-11
Information query
