Invention Grant
US08664359B2 Cancer related isoforms of components of transcription factor complexes as biomarkers and drug targets
失效
转录因子复合物组分的癌症相关同种型作为生物标志物和药物靶标
- Patent Title: Cancer related isoforms of components of transcription factor complexes as biomarkers and drug targets
- Patent Title (中): 转录因子复合物组分的癌症相关同种型作为生物标志物和药物靶标
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Application No.: US12598746Application Date: 2008-06-03
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Publication No.: US08664359B2Publication Date: 2014-03-04
- Inventor: Anna Kazantseva , Jekaterina Kazantseva
- Applicant: Anna Kazantseva , Jekaterina Kazantseva
- Applicant Address: US CA Los Angeles
- Assignee: OncoTx, Inc.
- Current Assignee: OncoTx, Inc.
- Current Assignee Address: US CA Los Angeles
- Agency: canady + lortz LLP
- Agent Karen S. Canady
- International Application: PCT/US2008/065688 WO 20080603
- International Announcement: WO2008/151200 WO 20081211
- Main IPC: C07K14/00
- IPC: C07K14/00 ; G01N33/53 ; G01N33/574 ; C07K14/435
Abstract:
The invention is related to isoforms of components of transcription factor complexes that are specifically expressed in cancer cells. These isoforms can be used as biomarkers for detection, diagnosis, prognosis and monitoring of treatments of cancer, and as drug targets of pharmaceutical compositions for the treatment of various cancers expressing the targeted isoforms. Methods, molecules, materials and kits for these uses are disclosed.
Public/Granted literature
- US20100087376A1 CANCER RELATED ISOFORMS OF COMPONENTS OF TRANSCRIPTION FACTOR COMPLEXES AS BIOMARKERS AND DRUG TARGETS Public/Granted day:2010-04-08
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