Invention Grant
US08664253B2 Imidazole derivatives useful as modulators of FAAH and as FAAH imaging agents
有权
咪唑衍生物可用作FAAH和FAAH显像剂的调节剂
- Patent Title: Imidazole derivatives useful as modulators of FAAH and as FAAH imaging agents
- Patent Title (中): 咪唑衍生物可用作FAAH和FAAH显像剂的调节剂
-
Application No.: US13254363Application Date: 2010-02-22
-
Publication No.: US08664253B2Publication Date: 2014-03-04
- Inventor: Ping Liu , Robert J. DeVita , Linus S. Lin , Marc D. Chioda , Terence G. Hamill , Wenping Li
- Applicant: Ping Liu , Robert J. DeVita , Linus S. Lin , Marc D. Chioda , Terence G. Hamill , Wenping Li
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp
- Current Assignee: Merck Sharp & Dohme Corp
- Current Assignee Address: US NJ Rahway
- Agent Maria V. Marucci; Valerie J. Camara
- International Application: PCT/US2010/024871 WO 20100222
- International Announcement: WO2010/101724 WO 20100910
- Main IPC: A61K31/4178
- IPC: A61K31/4178 ; A61K31/4439 ; C07D401/10
Abstract:
The present invention is directed to certain Inidazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.
Public/Granted literature
- US20120115894A1 IMIDAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH AND AS FAAH IMAGING AGENTS Public/Granted day:2012-05-10
Information query
IPC分类:
