Invention Grant
- Patent Title: Derivatives of pyridoxine for inhibiting HIV integrase
- Patent Title (中): 吡哆醇用于抑制HIV整合酶的衍生物
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Application No.: US13605502Application Date: 2012-09-06
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Publication No.: US08664248B2Publication Date: 2014-03-04
- Inventor: Brent Richard Stranix , Guy Milot , Jean-Emmanuel Bouchard
- Applicant: Brent Richard Stranix , Guy Milot , Jean-Emmanuel Bouchard
- Applicant Address: TW Taipei
- Assignee: TaiMed Biologics, Inc.
- Current Assignee: TaiMed Biologics, Inc.
- Current Assignee Address: TW Taipei
- Agency: Clark & Elbing LLP
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/62 ; C07D213/78
Abstract:
The present invention relates to methods of treating hepatitis C infection, HIV infection, AIDS, or AIDS-related complex, or inhibiting HIV replication by administering a compound of Formula I wherein: X is H or OH; Y is H or OH; R1 is H or halogen (F, Cl, Br, I); R2 is H or halogen (F, Cl, Br, I); R3 is H, C1-6 alkyl, C1-6 fluoroalkyl, or benzyl; R4 is H, C1-6 alkyl, or benzyl; and R5 is H or C1-6 alkyl; or pharmaceutically acceptable salts thereof, to a mammal.
Public/Granted literature
- US20120329827A1 DERIVATIVES OF PYRIDOXINE FOR INHIBITING HIV INTEGRASE Public/Granted day:2012-12-27
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