Invention Grant
US08664238B2 Indenoisoquinolinone derivatives, manufacturing method and medical use thereof
有权
茚并异喹啉酮衍生物，其制备方法和医疗用途
- Patent Title: Indenoisoquinolinone derivatives, manufacturing method and medical use thereof
- Patent Title (中): 茚并异喹啉酮衍生物，其制备方法和医疗用途
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Application No.: US13643314Application Date: 2009-12-16
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Publication No.: US08664238B2Publication Date: 2014-03-04
- Inventor: Hua Xiang , Tianlin Wang , Hong Xiao , Qidong You , Yao Yao , Xiaobo Li , Qingjiang Liao
- Applicant: Hua Xiang , Tianlin Wang , Hong Xiao , Qidong You , Yao Yao , Xiaobo Li , Qingjiang Liao
- Applicant Address: CN Nanjing, Jiangsu CN Nanjing, Jiangsu
- Assignee: China Pharmaceutical University,Nanjing Medical University Affiliated Brain Hospital
- Current Assignee: China Pharmaceutical University,Nanjing Medical University Affiliated Brain Hospital
- Current Assignee Address: CN Nanjing, Jiangsu CN Nanjing, Jiangsu
- Agency: Global IP Services
- Agent Tianhua Gu
- Priority: CN200910233991 20091022
- International Application: PCT/CN2009/075618 WO 20091216
- International Announcement: WO2011/047515 WO 20110428
- Main IPC: A61K31/473
- IPC: A61K31/473 ; C07D221/18
Abstract:
Indenoisoquinolinone derivatives (I), the manufacturing method and the medical use thereof, which belong to pharmaceutical chemistry and organic chemistry field, are disclosed. These compounds can be used for treating several medical symptoms related to postmenopausal syndrome, uterine fibers deterioration and aortic smooth muscle cells proliferation, especially ER-(+) depend breast cancer. Meanwhile, these compounds can also be used for treating glioma and lung cancer, and have inhibiting effect on tumor metastasis effect on tumor metastasis.
Public/Granted literature
- US20130085140A1 INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF Public/Granted day:2013-04-04
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