Invention Grant
US08664203B2 Thiazole derivatives and their use as P2Y12 receptor antagonists
有权
噻唑衍生物及其作为P2Y12受体拮抗剂的用途
- Patent Title: Thiazole derivatives and their use as P2Y12 receptor antagonists
- Patent Title (中): 噻唑衍生物及其作为P2Y12受体拮抗剂的用途
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Application No.: US13265493Application Date: 2010-04-21
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Publication No.: US08664203B2Publication Date: 2014-03-04
- Inventor: Eva Caroff , Kurt Hilpert , Francis Hubler , David Lehmann , Emmanuel Meyer , Dorte Renneberg
- Applicant: Eva Caroff , Kurt Hilpert , Francis Hubler , David Lehmann , Emmanuel Meyer , Dorte Renneberg
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: WOPCT/IB2009/051647 20090422
- International Application: PCT/IB2010/051742 WO 20100421
- International Announcement: WO2010/122504 WO 20101028
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/675 ; C07D417/04 ; C07F9/38
Abstract:
The present invention relates to thiazole derivatives of formula I and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
Public/Granted literature
- US20130281406A2 THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS Public/Granted day:2013-10-24
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