Invention Grant
- Patent Title: Ophthalmic compositions containing mucoadhesive polysaccharides able to promote corneal re-epithelization
- Patent Title (中): 含有能够促进角膜再上皮化的粘膜粘附多糖的眼科组合物
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Application No.: US12063623Application Date: 2006-08-10
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Publication No.: US08664197B2Publication Date: 2014-03-04
- Inventor: Patrizia Chetoni , Susi Burgalassi , Daniela Monti , Marco Fabrizio Saettone
- Applicant: Patrizia Chetoni , Susi Burgalassi , Daniela Monti , Marco Fabrizio Saettone
- Applicant Address: IT Corlo di Formigine (MO)
- Assignee: Opocrin S.p.A.
- Current Assignee: Opocrin S.p.A.
- Current Assignee Address: IT Corlo di Formigine (MO)
- Agency: Arent Fox LLP
- Priority: ITRM2005A0443 20050812
- International Application: PCT/IT2006/000616 WO 20060810
- International Announcement: WO2007/020671 WO 20070222
- Main IPC: A61K31/715
- IPC: A61K31/715 ; A61P27/04

Abstract:
Ophthalmic solutions containing arabinogalactans with a protective activity on the corneal epithelium, particularly suitable for use as artificial tears stimulating the recovery of corneal lesions and also particularly useful for contact lens users, containing from 1% to 10% by weight of arabinogalactan in an aqueous solution and possible other excipients, among which tonicity-adjusting agents, pH correctors, buffers and preservatives, except for benzalkonium chloride.The compositions according to the invention have a virtually negligible viscosity, but are sufficiently mucoadhesive to assure a considerable permanence time in the area of application. Besides being well-tolerated, the aforesaid compositions have considerable re-epithelization capacity.
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