Systems, methods, and computer program products are for managing APNs in a wireless communications network during a PDP context activation sequence. An exemplary method includes a radio network controller (RNC) generating an APN assignment request in response to a PDP context activation request being received from a device and sending the APN assignment request to an intelligent APN management system (iAPNMS). The method also includes determining, at the iAPNMS based upon an assignment factor, an APN to assign to the PDP context activation request and assigning the APN to the PDP context activation request. The method also includes one of the RNC and the iAPNMS modifying the PDP context activation request to include the APN, and the RNC forwarding the PDP context activation request including the APN to a serving general packet radio service (GPRS) gateway support node (SGSN) to continue the PDP context activation sequence.