Invention Grant
US08527211B2 Method to produce recombinant MBP8298 and other polypeptides by nucleotide structure optimization
有权
通过核苷酸结构优化生产重组MBP8298等多肽的方法
- Patent Title: Method to produce recombinant MBP8298 and other polypeptides by nucleotide structure optimization
- Patent Title (中): 通过核苷酸结构优化生产重组MBP8298等多肽的方法
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Application No.: US12457658Application Date: 2009-06-17
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Publication No.: US08527211B2Publication Date: 2013-09-03
- Inventor: Reza Zareie , Mahdi Abbasian
- Applicant: Reza Zareie , Mahdi Abbasian
- Agency: Choobin & Choobin Consultancy L.L.C.
- Agent Barry Choobin
- Main IPC: G01N31/00
- IPC: G01N31/00
Abstract:
A method for recombinant production of a polypeptide, exemplified by the therapeutic peptide MBP8298, by recombining and optimizing the nucleic acid encoding said polypeptide, expressing said nucleic acid in a microbial host cell, isolating said polypeptide from the host, and releasing embedded polypeptide from fusion partners or peptide concatamers are explained. Such method may provide increased production or simplified downstream processing for the polypeptide of interest.
Public/Granted literature
- US20110008827A1 Method to produce recombinant MBP8298 and other polypeptides by nucleotide structure optimization Public/Granted day:2011-01-13
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