Invention Grant
US08524656B2 GM-CSF and truncated CCL2 conjugates and methods and uses thereof 有权
GM-CSF和截短的CCL2缀合物及其方法和用途

  • Patent Title: GM-CSF and truncated CCL2 conjugates and methods and uses thereof
  • Patent Title (中): GM-CSF和截短的CCL2缀合物及其方法和用途
  • Application No.: US13003027
    Application Date: 2009-07-08
  • Publication No.: US08524656B2
    Publication Date: 2013-09-03
  • Inventor: Jacques GalipeauMoutih Rafei
  • Applicant: Jacques GalipeauMoutih Rafei
  • International Application: PCT/CA2009/000948 WO 20090708
  • International Announcement: WO2010/003240 WO 20100114
  • Main IPC: A61K38/00
  • IPC: A61K38/00 C12N15/62 C07K14/00
GM-CSF and truncated CCL2 conjugates and methods and uses thereof
Abstract:
A conjugate protein comprising a GM-CSF or a fragment thereof and a truncated CCL2 is described. The conjugate protein has unexpected immune suppressive, anti-obesity and tumoricidal properties and is useful in a variety of therapeutic applications.
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