Invention Grant
US08524494B2 Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
有权
低氧压力和BFGF在体外从成纤维细胞产生多能干细胞
- Patent Title: Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
- Patent Title (中): 低氧压力和BFGF在体外从成纤维细胞产生多能干细胞
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Application No.: US12547422Application Date: 2009-08-25
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Publication No.: US08524494B2Publication Date: 2013-09-03
- Inventor: Gail K. Naughton , Frank Ziegler , Mark Baumgartner , Kyle Nickey
- Applicant: Gail K. Naughton , Frank Ziegler , Mark Baumgartner , Kyle Nickey
- Applicant Address: US CA San Diego
- Assignee: Histogen, Inc.
- Current Assignee: Histogen, Inc.
- Current Assignee Address: US CA San Diego
- Agency: DLA Piper LLP (US)
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N5/00
Abstract:
The present invention is directed to a method of producing compositions including embryonic proteins. The method includes culturing cells under hypoxic conditions on a biocompatible surface in vitro. The culturing method produces both soluble and non-soluble fractions, which may be used separately or in combination to obtain physiologically acceptable compositions useful in a variety of medical and therapeutic applications.
Public/Granted literature
- US20100196963A1 CONDITIONED MEDIUM AND EXTRACELLULAR MATRIX COMPOSITIONS FROM CELLS CULTURED UNDER HYPOXIC CONDITIONS Public/Granted day:2010-08-05
Information query
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