Invention Grant
- Patent Title: Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea
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Application No.: US12940797Application Date: 2010-11-05
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Publication No.: US08524281B2Publication Date: 2013-09-03
- Inventor: Sripriya Venkata Ramana Rao , Syed Muzafar Shah , Christopher Richard Diorio , Maja Vencl-Joncic , Eugene James Murphy
- Applicant: Sripriya Venkata Ramana Rao , Syed Muzafar Shah , Christopher Richard Diorio , Maja Vencl-Joncic , Eugene James Murphy
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agency: Jones Day
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K35/00

Abstract:
The present invention provides an oral pharmaceutical formulation comprising coated spheroids of a kinase inhibitor such as neratinib, which formulation is designed to reduce or eliminate side effects associated with existing oral formulations of kinase inhibitors.
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