Invention Grant
US08524275B2 Pharmaceutical formulations containing opioid agonist, opioid antagonist and gelling agent 有权
含有阿片样物质激动剂,阿片拮抗剂和胶凝剂的药物制剂

Pharmaceutical formulations containing opioid agonist, opioid antagonist and gelling agent
Abstract:
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid.
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