Invention Grant
US08524248B2 Methods to diagnose and immunize against the virus causing human Merkel cell carcinoma
有权
用于诊断和免疫引起人类Merkel细胞癌的病毒的方法
- Patent Title: Methods to diagnose and immunize against the virus causing human Merkel cell carcinoma
- Patent Title (中): 用于诊断和免疫引起人类Merkel细胞癌的病毒的方法
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Application No.: US12808042Application Date: 2008-12-15
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Publication No.: US08524248B2Publication Date: 2013-09-03
- Inventor: Patrick S. Moore , Yuan Chang , Huichen Feng , Christopher Brian Buck , Diana V. Pastrana
- Applicant: Patrick S. Moore , Yuan Chang , Huichen Feng , Christopher Brian Buck , Diana V. Pastrana
- Applicant Address: US PA Pittsburgh US DC Washington
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US PA Pittsburgh US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2008/086895 WO 20081215
- International Announcement: WO2009/079481 WO 20090625
- Main IPC: A61K39/275
- IPC: A61K39/275 ; A61K35/12 ; A61K31/675 ; A61K31/7076 ; A61K38/21 ; A61K31/436 ; A61K31/7088 ; A61K38/16 ; C12Q1/70 ; C12Q1/68 ; C07H21/00 ; C07K14/065 ; C40B40/10 ; A61P31/20 ; A61P35/00 ; A61P37/04
Abstract:
The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases.
Public/Granted literature
- US20110135598A1 METHODS TO DIAGNOSE AND IMMUNIZE AGAINST THE VIRUS CAUSING HUMAN MERKEL CELL CARCINOMA Public/Granted day:2011-06-09
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