A real-time open domain speech translation system for simultaneous translation of a spoken presentation that is a spoken monologue comprising one of a lecture, a speech, a presentation, a colloquium, and a seminar. The system includes an automatic speech recognition unit configured for accepting sound comprising the spoken presentation in a first language and for continuously creating word hypotheses, and a machine translation unit that receives the hypotheses, wherein the machine translation unit outputs a translation, into a second language, from the spoken presentation.