Invention Grant
US08501927B2 Vaccine produced using optimized immobilization antigen cDNA of cryptocaryon irritans and producing method and use thereof
有权
使用隐孢子虫刺激素的优化固定抗原cDNA生产疫苗及其制备方法和用途
- Patent Title: Vaccine produced using optimized immobilization antigen cDNA of cryptocaryon irritans and producing method and use thereof
- Patent Title (中): 使用隐孢子虫刺激素的优化固定抗原cDNA生产疫苗及其制备方法和用途
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Application No.: US13239110Application Date: 2011-09-21
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Publication No.: US08501927B2Publication Date: 2013-08-06
- Inventor: Yen-Ling Tsai Song , Yen-Hong Lin , Jose Priya Thankaraj Alphonsal
- Applicant: Yen-Ling Tsai Song , Yen-Hong Lin , Jose Priya Thankaraj Alphonsal
- Applicant Address: TW Taipei
- Assignee: National Taiwan University
- Current Assignee: National Taiwan University
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C.
- Agent Anthony King
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00
Abstract:
The present invention provides an optimized immobilization antigen cDNA sequence of cryptocaryon irritans, which has been processed codon replacement and caused the cDNA to express in prokaryotic and eukaryotic cell and translate a protein has similar immunogenicity as the immobilization antigen purified from the theront of Cryptocaryon irritans. The present invention further provides a DNA vaccine produced using the cDNA to prevent fish form cryptocaryon irritans infection.
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