Invention Grant
US08501737B2 Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase
有权
哌嗪基，哌啶基和吗啉基衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 哌嗪基，哌啶基和吗啉基衍生物作为组蛋白脱乙酰酶的新型抑制剂
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Application No.: US12539682Application Date: 2009-08-12
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Publication No.: US08501737B2Publication Date: 2013-08-06
- Inventor: Kristof Van Emelen
- Applicant: Kristof Van Emelen
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agency: Woodcock Washburn LLP
- Priority: WOPCT/EP2003/014833 20021223
- Main IPC: A61K31/451
- IPC: A61K31/451 ; C07D239/24 ; C07D401/12 ; C07D413/12
Abstract:
This invention comprises the novel compounds of formula (I) wherein t, R1, R2, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20100009988A1 PIPERAZINYL-, PIPERIDINYL- AND MORPHOLINYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2010-01-14
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