Invention Grant
- Patent Title: Spiroaminodihydrothiazine derivatives
- Patent Title (中): 螺二氨基二氢噻嗪衍生物
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Application No.: US13055830Application Date: 2009-07-24
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Publication No.: US08501733B2Publication Date: 2013-08-06
- Inventor: Takafumi Motoki , Toshihiko Kaneko , Noboru Yamamoto , Afzal Khan
- Applicant: Takafumi Motoki , Toshihiko Kaneko , Noboru Yamamoto , Afzal Khan
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: WOPCT/JP2008/063516 20080728
- International Application: PCT/JP2009/063627 WO 20090724
- International Announcement: WO2010/013794 WO 20100204
- Main IPC: C07D513/10
- IPC: C07D513/10 ; A61K31/547
Abstract:
A compound represented by the general formula (I): or a pharmaceutically acceptable salt thereof, has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.
Public/Granted literature
- US20110152253A1 SPIROAMINODIHYDROTHIAZINE DERIVATIVES Public/Granted day:2011-06-23
Information query
