Invention Grant
US08501706B2 Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
有权
双链寡核苷酸复合物和通过RNA干扰进行基因沉默的方法
- Patent Title: Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
- Patent Title (中): 双链寡核苷酸复合物和通过RNA干扰进行基因沉默的方法
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Application No.: US13552709Application Date: 2012-07-19
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Publication No.: US08501706B2Publication Date: 2013-08-06
- Inventor: Christina Yamada , Anastasia Khvorova , Rob Kaiser , Emily Anderson , Devin Leake
- Applicant: Christina Yamada , Anastasia Khvorova , Rob Kaiser , Emily Anderson , Devin Leake
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C12N15/11
- IPC: C12N15/11
Abstract:
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.
Public/Granted literature
- US20120322855A1 Duplex Oligonucleotide Complexes and Methods for Gene Silencing by RNA Interference Public/Granted day:2012-12-20
Information query
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