Invention Grant
- Patent Title: Methods of generating embryoid bodies and uses of same
- Patent Title (中): 产生胚状体的方法及其用途
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Application No.: US12738086Application Date: 2008-10-05
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Publication No.: US08501474B2Publication Date: 2013-08-06
- Inventor: Galia Yirme , Joseph Itskovitz-Eldor
- Applicant: Galia Yirme , Joseph Itskovitz-Eldor
- Applicant Address: IL Haifa
- Assignee: Technion Research & Development Foundation Limited
- Current Assignee: Technion Research & Development Foundation Limited
- Current Assignee Address: IL Haifa
- International Application: PCT/IL2008/001318 WO 20081005
- International Announcement: WO2009/050694 WO 20090423
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02
Abstract:
Methods of generating embryoid bodies (EBs) by culturing embryonic stem cells (ESCs) under static conditions followed by culturing the cells under dynamic conditions using e.g., a Glass Bulb-shaped Impeller (GBI) or shaking a culture vessel are provided. Also provided are methods of generating expanded and/or differentiated cells from the EBs of the invention and methods of using same for treating disorders requiring cell replacement therapy.
Public/Granted literature
- US20100304486A1 METHODS OF GENERATING EMBRYOID BODIES AND USES OF SAME Public/Granted day:2010-12-02
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