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US08501412B2 Thermoelectric method of sequencing nucleic acids 失效
测序核酸的热电法

Thermoelectric method of sequencing nucleic acids
Abstract:
The present invention relates to a novel thermoelectric method for determining the sequence of nucleotides on a nucleic acid molecule through use of a thermopile and/or sequencing reagents flowing under the conditions of laminar flow. The methods disclosed herein involve the measurement of the heat generated by a deoxynucleotide incorporation event that can be accomplished without the need to control the temperature of any of a thermopile's junctions.
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