A ball lock clamp includes a cylinder housing. A first piston is movable in the cylinder housing in response to a first fluid pressure. A second piston is movable in the first piston. A rod extends from the first piston. A biasing member is positioned in the cylinder housing to provide a biasing force between the first piston and the housing. A plunger is at a terminal end of the rod. The plunger includes at least one ball moving radially in and out of the plunger. A receiver receives the plunger. The receiver retains the plunger in a locked position in the receiver. A mechanism releases the plunger from the receiver. The mechanism includes a member in the rod to move the at least one ball radially in and out of the rod.