Methods for targeting content based on user interests. A graphical user interface may be provided to a first user. A plurality of interest categories may be displayed to the first user through the graphical user interface. An indication of a first category selected from the plurality of interest categories may be received from the first user. Upon receiving the indication of the first category, a plurality of sub-categories of the first interest category may be displayed to the first user through the graphical user interface. Additionally, an indication of at least one selected sub-category chosen from the plurality of sub-categories may be received from the first user. A first plurality of content items based on the at least one selected sub-category may be selected. The first plurality of content items may be provided to the first user through the user interface.