Systems and methods for real time allocation of radio devices in a femtocell that includes a plurality of software-defined radios (SDRs) are provided. The SDRs can be reconfigured in real time based on the changing network conditions and/or changes to contractual obligations of the femtocell provider. The femtocell can be reconfigured in real time either remotely from a network operations center (NOC) or the femtocell can be configured to automatically detect changing usage patterns and to automatically reconfigure the SDRs. The femtocell can also be configured to receive emergency override signals from the NOC to cause the femtocell to reconfigure one or more of the SDRs for use by emergency responders.