Invention Grant
- Patent Title: Synthesis of prostanoids
- Patent Title (中): 前列腺素的合成
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Application No.: US13383764Application Date: 2010-07-13
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Publication No.: US08476471B2Publication Date: 2013-07-02
- Inventor: George Petros Yiannikouros , Panos Kalaritis , Chaminda Priyapushpa Gamage , Stephanie Bosse Abernathy
- Applicant: George Petros Yiannikouros , Panos Kalaritis , Chaminda Priyapushpa Gamage , Stephanie Bosse Abernathy
- Applicant Address: US SC Florence
- Assignee: Irix Pharmaceuticals, Inc.
- Current Assignee: Irix Pharmaceuticals, Inc.
- Current Assignee Address: US SC Florence
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- International Application: PCT/US2010/041825 WO 20100713
- International Announcement: WO2011/008756 WO 20110120
- Main IPC: C07C69/74
- IPC: C07C69/74

Abstract:
The presently disclosed subject matter provides a method of synthesizing prostaglandins and prostaglandin analogs comprising the ring closing metathesis of compounds of Formula (I). Also provided are novel compounds of Formula (I) and Formula (II). In addition to their use as synthetic intermediates in the presently disclosed methods, compounds of Formula (II) can be used as prostaglandin and/or prostaglandin analog prodrugs.
Public/Granted literature
- US20120165293A1 SYNTHESIS OF PROSTANOIDS Public/Granted day:2012-06-28
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