Invention Grant
- Patent Title: Modified AAV capsid polypeptides
- Patent Title (中): 改良的AAV衣壳多肽
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Application No.: US13322121Application Date: 2010-05-28
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Publication No.: US08476418B2Publication Date: 2013-07-02
- Inventor: Oliver Mueller , Hugo Katus , Karl Varadi , Jürgen Kleinschmidt
- Applicant: Oliver Mueller , Hugo Katus , Karl Varadi , Jürgen Kleinschmidt
- Applicant Address: DE Heidelberg DE Heidelberg
- Assignee: Deutsches Krebsforschungszentrum,Ruprecht-Karls-Universitat Heidelberg
- Current Assignee: Deutsches Krebsforschungszentrum,Ruprecht-Karls-Universitat Heidelberg
- Current Assignee Address: DE Heidelberg DE Heidelberg
- Agency: Foley & Lardner LLP
- Priority: EP09161375 20090528
- International Application: PCT/EP2010/057370 WO 20100528
- International Announcement: WO2010/136549 WO 20101202
- Main IPC: A61K38/02
- IPC: A61K38/02 ; A61K9/50
Abstract:
The present invention is concerned with the provision of a polynucleotide encoding an AAV capsid polypeptide comprising an inserted peptide and a vector comprising said polynucleotide. Moreover, contemplated is a host cell comprising said polynucleotide or vector, a method for the manufacture of said capsid polypeptide as well as said polypeptide. Further included is an antibody specifically binding to said polypeptide and a medicament comprising said polynucleotide, vector, polypeptide, or antibody. Also contemplated are the use of said polynucleotide, vector, polypeptide, or antibody for the manufacture of a medicament for the treatment of vascular disease and a method for the identification of a compound binding to said polypeptide.
Public/Granted literature
- US20120202732A1 MODIFIED AAV CAPSID POLYPEPTIDES Public/Granted day:2012-08-09
Information query
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