Invention Grant
- Patent Title: 3-hydroxy-5-arylisothiazole derivative
- Patent Title (中): 3-羟基-5-芳基异噻唑衍生物
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Application No.: US13392350Application Date: 2010-12-24
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Publication No.: US08476287B2Publication Date: 2013-07-02
- Inventor: Akihiro Okano , Naoto Kosuga , Munetaka Ohkouchi , Daido Hotta , Muneyoshi Makabe
- Applicant: Akihiro Okano , Naoto Kosuga , Munetaka Ohkouchi , Daido Hotta , Muneyoshi Makabe
- Applicant Address: JP Tokyo
- Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2009-295855 20091225; JP2010-043420 20100226
- International Application: PCT/JP2010/073464 WO 20101224
- International Announcement: WO2011/078371 WO 20110630
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/425 ; A61K31/4436 ; A61K31/4535 ; C07D239/24 ; C07D275/02 ; C07D417/02

Abstract:
[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of solving the problem]A compound of Formula (I): (where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, —NR7—; and R1 to R7 are specific groups),a salt of the compound, or a solvate of the salt or the compound.
Public/Granted literature
- US20120157459A1 NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE Public/Granted day:2012-06-21
Information query
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