Invention Grant
- Patent Title: Small molecule inhibitors of Lck SH2 domain binding
- Patent Title (中): Lck SH2结构域的小分子抑制剂
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Application No.: US12674685Application Date: 2008-08-18
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Publication No.: US08476273B2Publication Date: 2013-07-02
- Inventor: Jun Hayashi , Alexander Mackerell , Younus Mia , Guanjun Xia
- Applicant: Jun Hayashi , Alexander Mackerell , Younus Mia , Guanjun Xia
- Applicant Address: US MD Baltimore
- Assignee: University of Maryland, Baltimore
- Current Assignee: University of Maryland, Baltimore
- Current Assignee Address: US MD Baltimore
- Agency: Moore & Van Allen, PLLC
- Agent Marianne Fuierer
- International Application: PCT/US2008/073498 WO 20080818
- International Announcement: WO2009/026239 WO 20090226
- Main IPC: A61K31/501
- IPC: A61K31/501 ; A61K31/44 ; A61K31/16 ; A61K31/15
Abstract:
The present invention provides materials and methods for modulating an immune response. The materials and methods may be used to treat diseases associated with an aberrant immune response. In some embodiments, materials and methods of the invention may be used to treat autoimmune diseases, for example, rheumatoid arthritis.
Public/Granted literature
- US20110183984A1 SMALL MOLECULE INHIBITORS OF LCK SH2 DOMAIN BINDING Public/Granted day:2011-07-28
Information query
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