Invention Grant
- Patent Title: Method of reducing intraocular pressure in humans
- Patent Title (中): 降低人眼内压的方法
-
Application No.: US13072349Application Date: 2011-03-25
-
Publication No.: US08476247B2Publication Date: 2013-07-02
- Inventor: Norman N. Kim , William K. McVicar , Thomas G. McCauley , Prakash Jagtap
- Applicant: Norman N. Kim , William K. McVicar , Thomas G. McCauley , Prakash Jagtap
- Applicant Address: US MA Lexington
- Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee Address: US MA Lexington
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Cynthia L. Kanik
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H19/167 ; C07H19/173
Abstract:
Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing and/or controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).
Public/Granted literature
- US20110245195A1 METHOD OF REDUCING INTRAOCULAR PRESSURE IN HUMANS Public/Granted day:2011-10-06
Information query
