Invention Grant
US08476245B2 Inhibition of tumor growth and invasion by anti matrix metalloproteinase DNAzymes
有权
抑制肿瘤生长和抗基质金属蛋白酶DNA酶的侵袭
- Patent Title: Inhibition of tumor growth and invasion by anti matrix metalloproteinase DNAzymes
- Patent Title (中): 抑制肿瘤生长和抗基质金属蛋白酶DNA酶的侵袭
-
Application No.: US12390628Application Date: 2009-02-23
-
Publication No.: US08476245B2Publication Date: 2013-07-02
- Inventor: Tayebeh Pourmotabbed , Hisashi Hasegawa , Chad Batson
- Applicant: Tayebeh Pourmotabbed , Hisashi Hasegawa , Chad Batson
- Applicant Address: US TN Knoxville
- Assignee: University of Tennessee Research Foundation
- Current Assignee: University of Tennessee Research Foundation
- Current Assignee Address: US TN Knoxville
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The presently disclosed subject matter provides DNA molecules designed to down regulate the expression of MMP genes in a cell. Also provided are compositions comprising the DNA molecules. The presently disclosed subject matter further provides methods of using the DNA molecules to inhibit metastasis of a cancer cell. The presently disclosed subject matter also provides methods of using the DNA molecules to modulate tumor growth in a subject.
Public/Granted literature
- US20090227663A1 INHIBITION OF TUMOR GROWTH AND INVASION BY ANTI MATRIX METALLOPROTEINASES DNAZYMES Public/Granted day:2009-09-10
Information query
