A differential pressure sensor positioned adjacent a first pressure chamber and a second pressure chamber separated by a nozzle. Flow in a conduit is determined by detecting the pressure on either side of a nozzle. Changes in pressure are proportional to a change in flow. An integrated differential pressure sensor having different pressure detecting portions with strain gauges thereon detects differences in deflection of each pressure sensor portion resulting from change in fluid flow. A bridge circuit detects changes in the signals from the two different pressure sensor portions creating a differential which is proportional to a change in liquid flow. The present invention reduces the need for calibration of pressure sensors and improves the detection of fluid flow. The present invention has many applications and can detect small changes in fluid flow and is particularly applicable to the medical field where in many procedures, small fluid flows must be measured or determined accurately.