Methods and systems are provided for detecting presence of a target particulate of predetermined size (e.g., engine wear debris) in a fluid (e.g., an engine lubricant) by providing at least one pair of serially fluid-connected upstream test and downstream reference filtration elements in the fluid. At least the upstream test filtration element has a filtration size rating that is sufficient to remove a predetermined amount of the target particulate from the fluid. The differential pressure of the fluid may then be measured (e.g., by suitable pressure transducers) across each of the test and reference filtration elements. By comparing the differential pressure across the test filtration element to the differential pressure across reference filtration element, the presence of the target particulate in the fluid can thereby be detected by an increase in differential pressure across the test filtration element in comparison to the differential pressure across the reference filtration element. The methods and systems of the invention thus allow for the detection of target particulates that is independent of the fluid flow rate and/or temperature (viscosity, density).