A method for executing a mouse function of electronic device and an electronic device thereof are provided. In the present method, an amount and a relative position of input signals are detected by a sensor module. Then, whether the amount and the relative position are respectively conformed to a predetermined value is determined. If the predetermined values are conformed, whether the input signal is conformed to a specific signal is determined when a variation of the relative position is occurred. Finally, a corresponding mouse function is executed according to a type of the variation if the variation is conformed to the specific signal. As a result, a mouse device is no longer needed for a user to accomplish a directional operation on the electronic device so as to prevent inconvenience of particularly carrying a mouse device.