Invention Grant
US08445239B2 Fermentation processes for cultivating streptococci and purification processes for obtaining CPS therefrom
有权
用于培养链球菌的发酵方法和用于从其获得CPS的纯化方法
- Patent Title: Fermentation processes for cultivating streptococci and purification processes for obtaining CPS therefrom
- Patent Title (中): 用于培养链球菌的发酵方法和用于从其获得CPS的纯化方法
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Application No.: US12747914Application Date: 2008-12-19
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Publication No.: US08445239B2Publication Date: 2013-05-21
- Inventor: Paolo Costantino , Francesco Norelli , Francesco Berti , Roberto Olivieri , Giulia Bazzocchi , Concetta Maria Cicala , Silvia Fontani
- Applicant: Paolo Costantino , Francesco Norelli , Francesco Berti , Roberto Olivieri , Giulia Bazzocchi , Concetta Maria Cicala , Silvia Fontani
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Banner & Witcoff, Ltd.
- Priority: GB0818453.3 20081008
- International Application: PCT/IB2008/003729 WO 20081219
- International Announcement: WO2009/081276 WO 20090702
- Main IPC: C12P19/04
- IPC: C12P19/04
Abstract:
This invention is in the field of bacterial cultures and specifically relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from Streptococcus strains in fed batch culture and to novel purification methods suitable for production scale purification of bacterial capsular polysaccharides from Streptococcus strains resulting in higher levels of purity than previously obtained for production scale.
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