Invention Grant
- Patent Title: Hybridization device, methods, and system using mixing beads
- Patent Title (中): 杂交装置，方法和使用混合珠的系统
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Application No.: US12847570Application Date: 2010-07-30
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Publication No.: US08445201B2Publication Date: 2013-05-21
- Inventor: Bellon Laurent , Martin J. Goldberg , Robert J. Lipshutz , Kaliyur Narasimhan
- Applicant: Bellon Laurent , Martin J. Goldberg , Robert J. Lipshutz , Kaliyur Narasimhan
- Applicant Address: US CA Santa Clara
- Assignee: Affymetrix, Inc.
- Current Assignee: Affymetrix, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Alston & Bird LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12M1/34 ; C07H21/02 ; C07H21/04
Abstract:
A method, device and system for hybridizing a target oligonucleotide to at least one array comprising a plurality of mixing beads are provided. A target solution is mixed by agitating the mixing beads while the target oligonucleotides are hybridizing to the complementary probes on the array. In another embodiment, a permeable barrier contains the mixing beads, thereby preventing them from contacting the array surface.
Public/Granted literature
- US20110028352A1 HYBRIDIZATION DEVICE, METHODS, AND SYSTEM USING MIXING BEADS Public/Granted day:2011-02-03
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