Invention Grant
- Patent Title: Cartilage repair methods
- Patent Title (中): 软骨修复方法
-
Application No.: US11635265Application Date: 2006-12-07
-
Publication No.: US08444968B2Publication Date: 2013-05-21
- Inventor: Mitchell S. Seyedin , Matthew Matava
- Applicant: Mitchell S. Seyedin , Matthew Matava
- Applicant Address: US MO St. Louis
- Assignee: Isto Technologies, Inc.
- Current Assignee: Isto Technologies, Inc.
- Current Assignee Address: US MO St. Louis
- Agency: Polsinelli Shughart PC
- Main IPC: A01N65/00
- IPC: A01N65/00

Abstract:
The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.
Public/Granted literature
- US20070128155A1 Cartilage repair methods Public/Granted day:2007-06-07
Information query