Certain aspects of a method and system for supporting hardware acceleration for iSCSI read and write operations via a TCP offload engine may comprise pre-registering at least one buffer with hardware. An iSCSI command may be received from an initiator. An initiator test tag value, a data sequence value and/or a buffer offset value of an iSCSI buffer may be compared with the pre-registered buffer. Data may be fetched from the pre-registered buffer based on comparing the initiator test tag value, the data sequence value and/or the buffer offset value of the iSCSI buffer with the pre-registered buffer. The fetched data may be zero copied from the pre-registered buffer to the initiator.