In a method for diffusion-weighted acquisition of MR signals with an acquisition sequence that includes a diffusion module with multiple diffusion coding gradients and a readout module with readout gradients to acquire the MR signals, the acquisition sequence is configured to acquire MR signals that correspond to a predetermined signal coherence path. The method includes the acquisition of MR signals with the acquisition sequence, and the diffusion coding gradients are activated with predetermined gradient moments during the acquisition sequence. The gradient moments of the diffusion coding gradients are set such that MR signals that correspond to other coherence paths than the predetermined coherence path are reduced, wherein the adjustment of the gradient moments to achieve a predetermined reduction ensues on the basis of a threshold.