Invention Grant
US08436019B2 Sulfonyl-piperidin-4-yl methylamine amide analogs as GlyT1 inhibitors, methods for making same, and use of same in treating psychiatric disorders
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磺酰基 - 哌啶-4-基甲胺酰胺类似物作为GlyT1抑制剂，其制备方法及其在治疗精神疾病中的应用
- Patent Title: Sulfonyl-piperidin-4-yl methylamine amide analogs as GlyT1 inhibitors, methods for making same, and use of same in treating psychiatric disorders
- Patent Title (中): 磺酰基 - 哌啶-4-基甲胺酰胺类似物作为GlyT1抑制剂，其制备方法及其在治疗精神疾病中的应用
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Application No.: US12751576Application Date: 2010-03-31
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Publication No.: US08436019B2Publication Date: 2013-05-07
- Inventor: Craig W. Lindsley , P. Jeffrey Conn , Richard Williams , Carrie K. Jones , Douglas J. Sheffler
- Applicant: Craig W. Lindsley , P. Jeffrey Conn , Richard Williams , Carrie K. Jones , Douglas J. Sheffler
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Choate, Hall & Stewart LLP
- Agent Andrea L. C Robidoux; Dwight D. Kim
- Main IPC: A61K31/454
- IPC: A61K31/454 ; A61K31/445 ; A61P25/18 ; A61P25/22 ; A61P25/24
Abstract:
In one aspect, the invention relates to compounds which are useful as inhibitors of glycine type 1 transporter (GlyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GlyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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