Invention Grant
- Patent Title: Methods for suppressing activity of activated interferon-producing cells
- Patent Title (中): 抑制活化的干扰素产生细胞活性的方法
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Application No.: US11629045Application Date: 2005-06-09
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Publication No.: US08435530B2Publication Date: 2013-05-07
- Inventor: Jun Ohkawa , Yumiko Kamogawa
- Applicant: Jun Ohkawa , Yumiko Kamogawa
- Applicant Address: JP Tokyo
- Assignee: SBI Biotech Co., Ltd.
- Current Assignee: SBI Biotech Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Agent Antoinette F. Konski; Alex Y. Nie
- Priority: JP2004-173767 20040611
- International Application: PCT/JP2005/010561 WO 20050609
- International Announcement: WO2006/008886 WO 20060126
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C12N5/077
Abstract:
The present invention provides agents for regulating the activity of interferon-producing cells (IPCs), which comprise as active ingredients antibodies that bind to BST2 and/or to its homologues, and methods for regulating IPC activity that use these antibodies. According to the present invention, the ability of IPCs to produce interferons (IFNs) and the number of cells can be directly regulated. The present invention also provides uses of BST2 and/or its homologues as markers for IPC activation. Compounds that regulate IPC activation can be screened using the markers for IPC activation.
Public/Granted literature
- US20080305121A1 Agents for Regulating the Activity of Interferon-Producing Cells Public/Granted day:2008-12-11
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