Systems, methods and devices for modifying a patient adherence score which include, in one implementation, obtaining a patient profile in a patient population, the patient profile including multiple patient attributes and each patient attribute including a value; obtaining an adherence score for the patient profile for predicting patient adherence based on one or more of the multiple patient attributes wherein the adherence score indicates a likelihood of adherence of the patient to the prescribed treatment; and applying a modifier associated with an application to modify the adherence score obtained for the patient profile into a modified score for the application.