Invention Grant
- Patent Title: Synthetic microfluidic blood-brain barrier
- Patent Title (中): 合成微流体血脑屏障
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Application No.: US12726140Application Date: 2010-03-17
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Publication No.: US08417465B2Publication Date: 2013-04-09
- Inventor: Balabhaskar Prabhakarpandian , Kapil Pant , Shivshankar Sundaram , Ketan Harendrakumar Bhatt
- Applicant: Balabhaskar Prabhakarpandian , Kapil Pant , Shivshankar Sundaram , Ketan Harendrakumar Bhatt
- Applicant Address: US AL Huntsville
- Assignee: CFD Research Corporation
- Current Assignee: CFD Research Corporation
- Current Assignee Address: US AL Huntsville
- Agency: Maschoff Brennan
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space enabling formation of tight junctions similar to in vivo conditions using endothelial cells and brain cells.
Public/Granted literature
- US20110104658A1 Synthetic Microfluidic Blood-Brain Barrier Public/Granted day:2011-05-05
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