A system and method enable a wireless device to support simultaneously multiple push-to-talk (PTT) communications and interrupt certain PTT communication with higher priority ones. A user subscribes to multiple PTT communication groups and designates one of the groups as the primary group. The wireless device receives and plays PTT communications from the multiple PTT communication groups and interrupts playing of a PTT communication from a non-primary group if a PTT communication is received from the primary PTT communication group.